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The Role of Protein and Amino Acids in Sustaining and Enhancing Performance

June 11th, 2009

It is a commonly held belief that athletes, particularly body builders, have greater requirements for dietary protein than sedentary individuals. However, the evidence in support of this contention is controversial. This book is the latest in a series of publications designed to inform both civilian and military scientists and personnel about issues related to nutrition and military service.

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Effects of Protein Intake on Renal Function and on the Development of Renal Disease

One of the major functions of the kidney is the elimination Of the products of protein metabolism. It is not surprising, therefore, that protein intake exerts many diverse effects on the kidney. Most attention has been directed toward the role of protein intake in chronic renal failure. For at least a century, it has been known that reducing protein intake will ameliorate the symptoms of chronic renal failure, provided the reduction is not severe enough to induce protein deficiency. In recent years, much effort has been directed toward defining the optimum protein intake for patients with chronic renal failure, with the aim of slowing the rate of progression toward the end stage. Despite many reports, it is still not firmly established that protein restriction slows disease progression, although the bulk of available evidence supports this conclusion (for example, Fouque et al., 1992; Levey et al., 1996). In this review, however, attention will be limited to the effects of protein intake on the initiation of renal disease.

There are three ways in which protein intake may play a role in the development of renal disease: promotion of nephrolithiasis, enhancement of the morbidity of acute renal failure, and acceleration of glomerulosclerosis.

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